18 The use of CAM among patients in general is alarmingly high across the globe, with an increasing trend driven by various political 19 and socio-economic factors, health care system approachability, chronicity, and natural history of disease, 20 as well as physician-patient communication and health literacy. 21 , 22 REGULATIONS In the United States, the National Center for Complementary and Alternative Medicine (NCCAM), a center within the National Institutes of Health, is concerned with the practice of CAM and provides 'evidence-based' public discourse on various supplements, medicines, and practices.
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