Does the use of higher versus lower oxygen concentration improve neurodevelopmental outcomes at 18-24 months in very low birthweight infants?

[ 33 ] found a significant (pooled risk ratio (RR) 0.65 [95% confidence interval (CI): 0.43, 0.98]) or borderline significant (relative risk for mortality 0.62 [95% CI: 0.37–1.04]) reduction in mortality when a low (21–50% or 21–30%) compared to a high (> 50% or ≥ 60%) oxygen concentration was used for initial stabilization in preterm infants (≤ 37 or ≤ 32 weeks), respectively.

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