The difference between the learner and control groups in terms of success rate was highly significant after block 13 (Fig. 1e , significant p values: 0.047, 0.043, 0.002, 0.032, 0.004, 0.003, <0.001 for blocks 9, 14, 17, 18, 20, 21, 22 respectively) Interestingly, the assessment of the spine density of adult-born GCs revealed that, unlike the simple discrimination task, the complex task led to an increase in spine density after training (control group: 0.73 ± 0.19 spines/μm, n = 97 cells from 4 mice vs. learner group: 0.84 ± 0.25 spines/μm, n = 104 cells from 4 mice, p = 0.001 with the Student t -test, Fig. 1f, g ).
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Distinct forms of structural plasticity of adult-born interneuron spines in the mouse olfactory bulb induced by different odor learning paradigms.
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