An interesting trend from the SPPS data sets is the increased peptide complexity in terms of manufacturing, often due to more rigorous quality standards per phase of development (average length commercial and Phase 3 = 19; Phase 2 = 23; Phase 1 = 28).
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Process Mass Intensity (PMI): A Holistic Analysis of Current Peptide Manufacturing Processes Informs Sustainability in Peptide Synthesis.
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