Huntington disease update: new insights into the role of repeat instability in disease pathogenesis.

Med Genet · 2021 · PMC11006308 · PMID 38835439

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highly significantno p-value reported

Already more than 25 years ago a highly significant correlation between CAG instability and the size of the parental CAG repeat as well as somatic mosaicism in sperm was described for paternal transmission in HD [ 54 ].

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