123 Taking these three RCTs together, restarting OAC was associated with reduced risk of ischaemic stroke on the one hand but increased risk (of borderline significance) for recurrent ICH. 124 The threat of ICH recurrence is daunting but many physicians will consider restarting anti-thrombotic therapy at least 30 days after the ICH. 125 The results of ongoing RCTs focusing on OAC vs. no anticoagulation (without considering LAAC) in ICB patients with AF (such as EN
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Practical guide on left atrial appendage closure for the non-implanting physician: an international consensus paper.
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