The highly significant reductions in IL‐1β expression with RDN treatment led us to further investigate the NLRP3 inflammasome, where we saw reductions in all 3 inflammasome components (NLRP3, apoptosis‐associated speck‐like protein containing a caspase recruitment domain, and caspase‐1) in renal cortical tissue (Figure 2I ).
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Early Renal Denervation Attenuates Cardiac Dysfunction in Heart Failure With Preserved Ejection Fraction.
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