However, there was an increasing trend in the less rigid low birefringent (LB) collagen (suggesting type III collagen) in the adventitia and a decreasing trend in the more rigid high birefringent (HB) fibers (suggesting type I collagen) in the media in disturbed flow arteries treated with miR-204 mimic ( Supplementary Figure S6 ).
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Disturbed flow regulates protein disulfide isomerase A1 expression via microRNA-204.
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