A significant negative correlation was observed for both AHC (ρ = –0.329; P < 0.001) and HCV-related cirrhosis (ρ = –0.238; P < 0.001), suggesting that countries with higher initial incidences were more likely to experience a decreasing trend of incidence over time (Figure S4 in the Online Supplementary Document ).
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Epidemiology of acute hepatitis C and hepatitis C virus-related cirrhosis in reproductive-age women, 1990-2019: An analysis of the Global Burden of Disease study.
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The ASIR of AHC exhibited an increasing trend only in the high SDI regions (AAPC = 0.29; 95% CI = 0.16, 0.42) ( Figure 2 , panel A, Table 1 ).