Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia.

Highly significant (median p-value = 6×10 –7 ) pair-wise differences in molecular marker expression were observed for all markers ranging from mature, functional, and synaptic neuron markers to astrocyte, oligodendrocyte, and microglial markers ( Figure 1B ; Figure 1—figure supplements 4 and 5 ; Supplementary file 5 ) – confirming neuronal and non-neuronal cell-type identities in the NeuN + and NeuN - nuclei samples, respectively.

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