Longitudinal cognitive decline characterizes the profile of non-PD-manifest GBA1 mutation carriers.

NPJ Parkinsons Dis · 2024 · PMC11035543 · PMID 38649346

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

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boldest claim

The sentences

just missed significancep = 0.051so close (0.05 < p ≤ 0.1)

Longitudinal analyses LMEM showed a significantly higher annual increase of the MDS-UPDRS III bradykinesia subscore of the GBA1 NMC group compared to the GBA wildtype group (+1.13, 95% CI: −0.01–+2.26, p = 0.048; Table 2 ), but just missed significance level after adding age as a fixed factor remaining as a trend (+1.11, 95% CI: −0.06–+2.22, p = 0.051).

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