Natural killer cell subsets and their functional molecules in peripheral blood of the patients with breast cancer.

Immun Inflamm Dis · 2024 · PMC11037257 · PMID 38652012

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

borderline significancep = .06so close (0.05 < p ≤ 0.1)

Comparing frequencies of different NK cell subsets, the results revealed a borderline significance in the lower percentage of conventional cytotoxic NK cells with CD3 − CD56 dim CD16 + phenotype (9.88 ± 1.30 vs. 12.44 ± 1.49, p = .06) and a higher percentage of tolerant NK cells with CD3 − CD56 + CD27 − CD11b − phenotype (0.82 ± 0.13, 0.48 ± 0.10, p = .06) in peripheral blood of the patients compared to the HDs.

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a nonsignificant trendno p-value reported

This finding was observed as a nonsignificant trend when considering total NK cells but significant in case of conventional regulatory (7.65 vs. 11.12) as well as dysfunctional NK cells (9.08 vs. 19.65).

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