Common P-glycoprotein (<i>ABCB1</i>) polymorphisms do not seem to be associated with the risk of rivaroxaban-related bleeding events: Preliminary data.

Even if variant alleles on different loci “favored” different (hypothetical) effects, it is the “net” effect of the entire set-up across the four polymorphisms that would be informative: an increasing trend in bleeding incidence across such a “variant gradient” would indicate their practical relevance.

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