Meningioma achieves malignancy and erastin-induced ferroptosis resistance through FOXM1-AURKA-NRF2 axis.

3 Results 3.1 AURKA levels show an increasing trend with higher grade meningiomas Three Meningioma-related GEO datasets, GSE74385 , GSE16581 and GSE136661 were obtained for differentially express genes (DEGs) analysis between WHO grade III and grade I tumors, the DEGs were visualized as Volcano Plots ( Fig. 1 A). 22 overlapped DEGs were identified, with 6 downregulated and 16 upregulated ( Fig. 1 B).

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