While neither MMP9 nor IGF1 were significantly differentially expressed in our MSC-EV-treated OACs after 24 h of co-culture, the levels of MMP9 showed a positive trend, and it would be interesting to assess the expression profiles of migration-related genes over a longer period of MSC-EV treatment.
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Functional and Molecular Analysis of Human Osteoarthritic Chondrocytes Treated with Bone Marrow-Derived MSC-EVs.
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