Integrated Omics Analysis Uncovers the Culprit behind Exacerbated Atopic Dermatitis in a Diet-Induced Obesity Model.

Among the lipid transporter genes, the expression of genes involved in the transport of fatty acids, namely, solute carrier family 26 (fatty acid transporter) member 4 ( Slc27a4 , p = 0.059), showed an increasing trend, but this was not statistically significant, whereas genes associated with the transport of phospholipids, such as ATP-binding cassette subfamily member 1 ( Abca1 , p < 0.05) and scavenger receptor class B member 1 (Scar1 , p < 0.005), exhibited a significant upregulation in the HF + AD group ( Figure 6 A,B).

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