Silibinin's Effects against Methotrexate-Induced Hepatotoxicity in Adjuvant-Induced Arthritis Rat Model.

Pharmaceuticals (Basel) · 2024 · PMC11054686 · PMID 38675395

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The present study showed a highly significant reduction in the cellular GSH levels after the MTX treatment, indicating an imbalance between antioxidants and pro-oxidants in the liver ( Figure 9 B).

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