Calcium Chloride as a Novel Stabilizer for Foot-and-Mouth Disease Virus and Its Application in the Vaccine Formulation.

The result measured by the PaSTRy method exhibited an increasing trend in T m values up to 10 mM calcium and a decreasing trend in T m values above 30 mM calcium, which is consistent with previous reports that treatment with 0.5 M calcium resulted in lower T m values than the untreated control [ 27 , 46 ].

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The thermal stability of FMDVs increased up to a CaCl 2 concentration of 10 mM, and it had a decreasing trend at >30 mM.

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