Ponatinib Induces a Procoagulant Phenotype in Human Coronary Endothelial Cells via Inducing Apoptosis.

We found that ponatinib treatment did not enhance F3 mRNA level ( Figure 6 A) but the level of THBD mRNA was decreased ( Figure 6 B) and the effect was of borderline significance at 50 ( p = 0.0513) and 150 nM ( p = 0.0737).

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