borderline significancep < 5 × 10 −6
Since the sample size of personality was not large enough, to get more SNPs, all the exposed genetic IVs were identified at least borderline significance ( p < 5 × 10 −6 ) 25 , and clumped at the threshold of linkage disequilibrium (LD) ( r 2 < 0.001 within 10,000 kb).