TRPV2 modulates mechanically Induced ATP Release from Human bronchial epithelial cells.

Maximal ATP release observed with 100 CPM FSS showed a decreasing trend ( P < 0.05) with TRPV2 siRNA knockdown in PBECs (vehicle: 197 ± 24.52 nM, siRNA: 119 ± 26.85 nM) (Fig. 5 e), equivalent to a 35.82% decrease in ATP release (Fig. 5 f).

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