Upon tivozanib treatment, both Ca9-22 and CAL-27 cells displayed an increasing trend in the proportion of cells arrested in the G2 phase, and this was found to be dose-dependent ( Fig. 1D ).
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Tivozanib-induced activation of the mitochondrial apoptotic pathway and suppression of epithelial-to-mesenchymal transition in oral squamous cell carcinoma.
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