The quantitative genetics of gene expression in Mimulus guttatus.

If we regress the alt-allele frequency in reads from heterozygotes (y-axis of Fig 3B ) onto the estimates for both a and d simultaneously, both are highly significant as positive predictors of allele frequency (p < 10 −9 for each coefficient).

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For cis eQTLs, this test provides only one gene with a compelling case for over/under dominance: MgIM767.14G274100.v1.1, a pectin acetylesterase protein, is highly significant for overdominance in three families and marginally significant in a fourth.

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