Identification of people with Lynch syndrome from those presenting with colorectal cancer in England: baseline analysis of the diagnostic pathway.

The rationale for identifying LS carriers is further enhanced by the demonstration of a 50% reduction in their CRC incidence following daily aspirin [ 20 ] (now also a NICE guideline) [ 21 ], and the highly significant reduction in their non-CRC LS-associated cancer risk when prescribed dietary supplementation with resistant starch [ 22 ].

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