In TCGA-KIRC database, UBB levels showed a decreasing trend in tumor tissue compared to nontumor tissue, which was consistent with the results for the Gene Expression Omnibus (GEO) datasets ( GSE53000 , GSE53757 ) (Fig. 1A ).
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Downregulation of UBB potentiates SP1/VEGFA-dependent angiogenesis in clear cell renal cell carcinoma.
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