We further observed that baicalein significantly and dose‐dependently reduced the elevated expression of Maob (Figure 4A ; p = 0.0329 and 0.0108 for 10 and 100 μM of baicalein, respectively) and Serpina3n (Figure 4C ; p = 0.0073 and 0.0583 for 10 and 100 μM of baicalein, respectively), while Lcn2 and C3 also showed a decreasing trend (Figure 4B,D ).
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Baicalin and baicalein from Scutellaria baicalensis Georgi alleviate aberrant neuronal suppression mediated by GABA from reactive astrocytes.
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