Safety and feasibility of chemotherapy followed by liver transplantation for patients with definitely unresectable colorectal liver metastases: insights from the TransMet randomised clinical trial.

Indeed, 19 out of 21 patients in the Norwegian study experienced tumour relapse, which is a highly significant recurrence rate, although mitigated by preoperative staging inaccuracies rather than true recurrences in some patients. 24 Independent risk factors have also been shown to be useful in optimising patient selection and improving survival. 20 Obviously, the selection criteria in our study were more stringent, excluding tumour progression, high CEA levels and BRAF mutation.

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