Bile acid and nonalcoholic steatohepatitis: Molecular insights and therapeutic targets.

J Adv Res · 2024 · PMC11081971 · PMID 37356804

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a decreasing trendno p-value reported

In a phase 2 DBRCT [134] , in the 100 mg group treated with cilofexor, total and primary serum bile acids decreased moderately while secondary bile acids decreased significantly, with no alteration in liver stiffness but a decreasing trend of fibrosis-associated markers in serum, TIMP-1.

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