Barely Significant
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Loss-of-Function Variant in the SMPD1 Gene in Progressive Supranuclear Palsy-Richardson Syndrome Patients of Chinese Ancestry.

J Mov Disord · 2024 · PMC11082598 · PMID 38291878

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hedged sentence
0.0000
closest p · 0.0× alpha
0.0000
boldest claim

The sentences

highly significantp = 1.25 × 10 -15actually significant
[ 12 ] also showed a strong and highly significant association between SMPD1 variants with ≥ 56% loss of enzymatic activity and PD risk (OR 2.24, p = 1.25 × 10 -15 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.