Oleocanthal Protects C2C12 Myotubes against the Pro-Catabolic and Anti-Myogenic Action of Stimuli Able to Induce Muscle Wasting <i>In Vivo</i>.

As for MuRF-1 protein expression, the myotubes exposed to CM-C26 or TNF-α showed an increasing trend, which was restored to the Co values when OC was also present in the culture medium at both 24 and 48 h ( Figure 2 ).

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As for MyoG levels, they were significantly reduced by TNF-α at a 48 h treatment time, while only a decreasing trend could be observed for CM-C26.

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