a decreasing trendp=0.011
However, there was a difference in the pre-PDSA cycles, with the opioid stewardship programme hospital presenting higher inpatient opioid consumption (average of 16 mg oral morphine equivalents higher; 95% CI 5 to 27; p=0.008) but a decreasing trend of −2 mg oral morphine equivalents per month (95% CI −4 to –0.6; p=0.011) compared with the control hospital.