Thus, systemic treatment, even if highly dosed, might have failed to provide sufficient local levels of dexamethasone to result in such subtle effects, especially since a small trend towards inhibition could be observed in this trial as well (DBF ring ≈ 12%, Flare area ≈ 13%).
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Glucocorticoids Do Not Affect the Vascular Component of TRP-Mediated Neurogenic Skin Inflammation.
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