Resident gut microbiota community determines the efficacy of soluble fiber in reducing adiposity.

Food intake and body weight In the responder study, repeated-measures ANOVA of daily food intake revealed a highly significant effect of diet, time, and their interactions (all p < 0.001; Figure 1A ), where rats fed the soluble dietary fibers GLUC (10% w/w oat beta-glucan), FOS (10% w/w fructooligosaccharides), and PECT (10% w/w pectin) each had significantly lower daily food intakes relative to those fed either 5% (CONT) or 10% (CELL) w/w cellulose control diets ( Figure 1A ).

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