Exploring novel immunotherapy biomarker candidates induced by cancer deformation.

PLoS One · 2024 · PMC11093347 · PMID 38743676

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an increasing trendno p-value reported

Interestingly, through qPCR validation, we were able to confirm that CRLF2, SORCS2, SORL1, IL7R, CSF2RA, LRIG1, SIRPA, MDGA1, IL1R1, PSG5, and PDGFRB all exhibited an increasing trend in expression during cancer deformation ( Fig 3B ).

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a decreasing trendno p-value reported

The RNA sequencing analysis confirmed that additional genes, specifically CD33, LILRB1, LRRN1, IL13RA2, and NDNF, exhibited a decreasing trend as Ig genes, as illustrated in the violin plot in Fig 4B .

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