Reconstitution and characterization of BRAF in complex with 14-3-3 and KRAS4B on nanodiscs.

K D values obtained for tagless BRAF (mean ± SD for dimer: 25.5 ± 4.1 nM, n = 4; monomer: 35.5 ± 0.4 nM, n = 2) were similar to those for MBP‐BRAF (Table 1 ), with negligible or marginally significant differences (dimer: p = 0.164, monomer: p = 0.0464).

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