PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis.

p values less than 0.05, 0.01, and 0.001, respectively, signify significant (* or # ), very significant (** or ## ), and extremely significant (*** or ### ) differences. 10.7554/eLife.95815.3.sa0 eLife assessment Steiner Laurie Reviewing Editor University of Rochester Medical Center United States Compelling Fundamental This fundamental work significantly advances our understanding of how FOG1 nuclear localization is regulated during erythropoiesis and megakaryopoiesis, including the role of EPO and MPL/TPO signaling in this process.

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