HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes.

Nat Commun · 2024 · PMC11126580 · PMID 38789411

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highly significantno p-value reported

mRNA expression analysis showed that inactivation of the CHRs in the BUB1 and CCNB2 promoters led to a highly significant loss of repression of the specific gene when the cells were arrested with Idasanutlin.

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