3a ), H7.HK2 in combination with H7.HK4 mouse IgG2a did not improve the body weight trough from day 4–6 post challenge as both groups fully protected mice from death with up to 7-8% weight loss; the mAb combination demonstrated a statistical trend and then significance for improved recovery of weight loss starting on day 7 post challenge (Fig. 3a ).
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Human neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head.
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