highly significantP = 0.001
Similar results were obtained for the whole-plaque cohort (stable and unstable plaque), where CCR6 showed a highly significant (P = 0.001) correlation with CCL18 levels (data not shown) when taking all plaques.
Similar results were obtained for the whole-plaque cohort (stable and unstable plaque), where CCR6 showed a highly significant (P = 0.001) correlation with CCL18 levels (data not shown) when taking all plaques.
Of the chemokine receptors tested, only CCR6 showed borderline significant correlation with CCL18 (p = 0.055); its expression was highly correlated with T-cell presence.
In this case, CCL18 administration also led to plaque expansion, albeit at borderline significance ( Figure 2H ).