Barely Significant
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Effect of an intravenous acetaminophen/ibuprofen fixed-dose combination on postoperative opioid consumption and pain after video-assisted thoracic surgery: a double-blind randomized controlled trial.

Surg Endosc · 2024 · PMC11133211 · PMID 38609589

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an increasing trendno p-value reported
Although the prescription of non-opioid analgesics showed an increasing trend during the study period, the number of patients receiving a combination of two or more non-opioid analgesics remained low [ 22 ].

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