Multivariate Analysis of Individual Bacterial Outer Membrane Vesicles Using Fluorescence Microscopy.

As a positive control, the presence of OmpA in the OMV fractions was also detected by Western blotting, and the results showed that OmpA was present in all fractions, while a notable trend of increasing LtxA level with OMV size was observed ( Figure 6 c).

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18 , 19 The intriguing heterogeneities observed in OMV structure and composition suggest that there may be significant differences in function and immunological properties between different types of OMVs.

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