Maternal and perinatal health indicators in Brazil over a decade: assessing the impact of the COVID-19 pandemic and SARS-CoV-2 vaccination through interrupted time series analysis.

ationary; the indicators Perinatal Mortality Rate (MPC: −0.10; 95% CI: −0.13, −0.08), Preterm Birth Rate (MPC: −0.03; 95% CI: −0.06, −0.01) and, Apgar score <7 at the 1st minute rate (MPC: −0.14; 95% CI: −0.16, −0.12), and Apgar score <7 at the 5th minute rate (MPC: −0.18; 95% CI: −0.20, −0.16) had a decreasing trend; and the indicator Low birth weight rate (MPC: 0.04; 95% CI: 0.02, 0.05) had an increasing trend ( Table 1 ).

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rth Rate (MPC: −0.03; 95% CI: −0.06, −0.01) and, Apgar score <7 at the 1st minute rate (MPC: −0.14; 95% CI: −0.16, −0.12), and Apgar score <7 at the 5th minute rate (MPC: −0.18; 95% CI: −0.20, −0.16) had a decreasing trend; and the indicator Low birth weight rate (MPC: 0.04; 95% CI: 0.02, 0.05) had an increasing trend ( Table 1 ).

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