Genome, HLA and polygenic risk score analyses for prevalent and persistent cervical human papillomavirus (HPV) infections.

Eur J Hum Genet · 2024 · PMC11153215 · PMID 38200081

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In adjusted models, four HLA alleles, DRB1*15:03, DRB1*13:02, DQB1*05:02 and DRB1*03:01, were significantly associated with persistent hrHPV in the ACCME cohort; DRB1*03:01 and DQB1*02:01 remained borderline significant in the PACS cohort; and DRB1*15:03, DRB1*13:02, DRB1*03:01 and DQB1*06:02, were significantly associated with persistent hrHPV in the combined cohort analysis (Table 2 ).

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