23 On the other hand, a positive trend is reflected by the surface concentration at the interphase, Γ values, that increased in the samples based on mixed micelles (up to 9 × 10 –7 mol m –2 in the case of P188/P407). 23 The surface area occupied by one surfactant molecule has significantly ( p < 0.05) decreased (from 5 to 2 nm 2 ) in mixed micelles, demonstrating tighter organization of Poloxamer molecules at the phase boundary and more effective adsorption.
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Poloxamer-Based Mixed Micelles Loaded with Thymol or Eugenol for Topical Applications.
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