Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia.

Interestingly, there was a moderate but highly significant increase in PLT counts of JAK2 +/VF mice ( JAK2 +/VF : 1519 ± 59 10 9 /L; JAK2 +/+ : 1146 ± 58 10 9 /L) in both male and female mice (Fig. 1 F and Additional file 3: Fig.

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