Finally, we identified a suggestively stroke-associated TRPM2-AS promoter ( p -value = 5.78 × 10 –6 ) with borderline significant replication in T1D, which we validated with an in vitro cell-based assay.
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Whole-genome sequencing identifies variants in ANK1, LRRN1, HAS1, and other genes and regulatory regions for stroke in type 1 diabetes.
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