Prevalence and prognostic importance of exercise limitation and physical inactivity in COPD.

Several studies have demonstrated that a low exercise capacity, as assessed by peak V̇ O 2 during a cardiopulmonary exercise test (CPET) (<593–654 mL·min −1 or <10.5–14.6 mL·kg −1 ·min −1 ), is a highly significant predictor of mortality, independent of forced expiratory volume in 1 s and age [ 23 – 26 ].

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