Inhibition of astroglial hemichannels prevents synaptic transmission decline during spreading depression.

Biol Res · 2024 · PMC11167948 · PMID 38867288

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Moreover, while Gap19 (300 μM) significantly decreased the IOS in the initiation phase, it led to an increasing trend in the IOS during the spreading phase, particularly closer to the high [K + ] stimulation site (Fig. 3 A–C).

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