Optimization of Flavonoid Extraction from <i>Abelmoschus manihot</i> Flowers Using Ultrasonic Techniques: Predictive Modeling through Response Surface Methodology and Deep Neural Network and Biological Activity Assessment.

Additionally, the ANOVA results of the model revealed that the effects of ethanol volume fraction, solid-to-liquid ratio, and extraction time on CE were highly significant ( p < 0.001).

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The extraction rates displayed an increasing trend within the 10 to 30 min range, peaking at 30 min and subsequently decreasing between 30 and 50 min.

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