a decreasing trendp = 0.05
Finally, in the old groups, our investigations revealed that p16 exhibited a decreasing trend when comparing the control with the treated cells; in particular, p16 expression was significantly reduced in the fibroblasts treated with both CP ( p = 0.05) and Voghera pepper extracts ( p = 0.02) ( Figure 9 , Panel Z, right) ( Table 7 ). 3.6.